Clay,

Lots of really good Fly Fishing podcasts out there. I'm currently subscribed to the following:

1. Fly Fish Radio http://www.flyfishradio.com/podcast.php
-- From what I can see this podcast isn't being updated as often as it used to be.
2. Itinerant Angler http://www.itinerantangler.com/podcasts/podcasts/
-- My personal favorite podcast on fly fishing, hands down. Zach Mathews is a wonderful host and he has really invested in the podcast and it sounds extremely professional as a result.

There is also a video podcast out there that is all about fly tying. I can't put my finger on the link right now, but will update when I get home this evening (haven't synced my iPod since I subscribed to this one). From within iTunes you can choose Podcasts and then do a search for Fly Fishing podcasts (or search for one of the above listed and choose the "others like this" option).

Brian