I dont worry about how a rod/reel balances in my hand either. What I do worry about is how the combo actually "feels" in my hand when line is out the rod tip and I'm casting it at the normal distances I fish that particular rod/reel. Once you get line out the tip guide, all the balancing stuff with the line all spooled on the reel, sitting in your house, goes out the window, somewhat. I have one rod that actually feels better with a heavier reel on it at my normal casting distance. A lighter reel on it tires my hand/wrist/arm faster (swing weight) as it's then quite tip-heavy. I also have another rod that likes a light reel for my tastes, lightest reel I have.
I gotta get out and fish a rod/reel combo a little to really know what that particular rod/reel combo needs.