I fish for them regularly.
Best places are: Tail-races below the dam, off of sandy points with a drop-off, edge of channel, anywhere you find schools of shad!
Best times are: Spring-early, up to mid-day, and evenings, especially near river mouths and inlets.
Summer-Early morning, evening and night, near drop-off shelves. Fall Most of the day and night, anywhere there are schools of shad. Look for diving seagulls and fish under them. Winter- All day. Look for schools of shad. Stripers love cold water and are one of the most active winter fish down south. Follow flocks of seagulls, especially when you see them diving. There are shad there, most likely, and almost guaranteed stripers and white bass underneath them!
Equipment: Do not use anything less than an 8 wt rod, preferably with a fighting butt. Have a large fly reel with a disc-drag and LOTS of backing…you’ll need it. I use a shooting taper, but any weight-forward line will work. Use a short, heavy tapered leader-7’ is plenty. I even do some spey casting for them. If you like fishing with it, even a sink tip line works. Pretend you are fishing for tarpon and you’ll be pretty close.
Flies: Anything that resembles a shad, or bluegill, tied on stout streamer hooks, usually size 6 and up, or better yet, use salt-water hooks. I tie several versions of Puglisis-style flies and color them to match shad and bluegills. They hit them with murderous abandon when they are attacking shad schools. Behind the tail-races, another fly that works good for me is a large wooley-bugger in size 6 or 4, with the front 1/3rd red and the rest white. All of your files should be tied weighted.
Cast into any group of jumping baitfish or under any flock of wheeling water birds, and if you get a chance (most of the time, it will get hammered as soon as it hits), twitch it slightly after a few seconds. Strikes will be vicious and sudden. Set the hook HARD, and REPEATEDLY (stripers have a hard mouth). Then, for the first run, just hang on. You won’t stop or turn the fish, trust me. After about 50-100 yards, the striper will usually slow down and maybe turn. Then you can start working the fish in, but be ready, because the fish will take several more runs of shorter length, very suddenly. The last one will be when the fish sees you, about the time your are reaching for it to remove it from the water. You are usually off-balance and not ready, so take that into account. This is fresh-water Big-Game fishing at it’s best.
If you can’t find any shad or birds, and don’t have a fish-finder, then work your fly along the shelf of drop-offs near sandy points, and along rip-raps.
Good Luck,
Semper Fi!