I fish flouro tippet pretty much exclusively for trout. 75% of which is 6x. I carry 5x thru 7x. I fish it both dry and wet on a furled thread leader. I preferred the Orvis Maxknot....but it's discontinued now. Not sure what I will go to when my 3-4 spools of each size run out. It will be flouro though most likely. I've seen too many times where it did make the difference.