Re: One fly to rule them all....
Believe it or not, for me it would be a #14, #16 or #18 Stimulator. I know it's generally thought of as a western pattern, but it has been incredibly effective for me here in PA as a searching pattern. Last year I was frustrated fishing a midge hatch. The midges that were hatching were probably a size #28 or maybe even #30. The trout continually refused the smallest midge patterns I had, which were #26. I decided to just try something stupid in the hopes that there might be a dumb fish out there and I tied on a #14 Stimulator. The fish actually went crazy for it. I ended up catching a fourteen inch rainbow on that fly that day. Believe me, there was nothing even close to that size or profile hatching on that stream that day, and there surely wasn't anything that color (it had a flo. orange body with a flo. lime green head).
-Darryl
My one wish is that when I die my wife doesn't sell my fishing stuff for what I told her I paid for it...