Nope I tie #22 Doc Spratleys, gnats, wooly buggers PTN etc all the time and put everything there that should be there.

I do tie almost all of Al Campbell's too simple flies, that might be a suggestion for you. They only have the bare minimum to start with. A bloodworm is only red thread with a black or brown thread head. There are lots of patterns with using only thread such as a thread ant.