There is no doubt that hand-tied leaders work better for nymphing, either high-stick/Euro/whatever or with an indicator. I now tie all mine.
Basic formula for a ten-foot leader suitable for 5-7wt lines, which is about right most of the time around here:
4 feet of 30lb Maxima Chameleon
6" 20lb Maxima Chameleon
6" 15lb Maxima Ultragreen
4 feet of 1X standard mono
Tippet ring or micro-swivel
1 foot of 2X to 3X mono or fluoro. Shot, if required, go above the tippet ring/swivel.
I have also started playing with subbing two sections of Amnesia for the short tapered section to function as "sighters" for high-sticking. They work.
Owner, Yellowstone Country Fly Fishing
Head Guide, Parks' Fly Shop
Fly Designer, Montana Fly Company
Author, Yellowstone Country Flies and River Characters