Late May is prime time, you will need March Browns, Grey Fox, large sulphurs (#14) and an assortment of caddis. Hendricksons, and Paraleps should be over. Probably too early for the Green Drakes and large Olives, but wouldn't hurt to have a few in your box. Pretty crowded up that way then, but you will find water to fish. As long as the West Branch is under 700 cfs it's very wadeable. As well as Dette Flies stop and see Dennis at Catskill Flies, both are quite knowledgeable of what's going on. Enjoy the area, it's a very special place. You will have one less person to contend with, I'll be in Colorado fishing for 10 days, end of May to early June.

Gene