I had a rotator cuff problem in my right shoulder a couple of years ago, so I switched hands, and converted my reels to right hand retrieve. Casting was not a problem. I relearned very quickly. The wheels came off, however when playing a fish, or mending line. Both seemed very clumsy, and I lost a lot of fish right at the net. Shoulder is better now, so U'm back to normal.

Note to Hickoryshad. If you let that rotator cuff problem go too far, it may become unfixable.