I've almost totally stopped using Uni 8/0 except to finish up my existing stock. I have found MFC 8/0 a thread I'm most comfortable with for all around tying. If I need something finer I agree with Byron Veevus 16/0 is very good. I like a thread that lays flat without having to untwist probably the reason I will not switch to a heavier Veevus. All this is probably because I tied for years with Danville 6/0, and still do for many patterns.
Gene