Thanks all for the replies. Keep them coming.

Byron:

Late October is a good time to be there as it's usually less crowded, colorful, and both rainbows and browns are false-spawning. Fish eggs, scuds, and San Juans, though you might get a BWO or midge hatch in the afternoon or evening. The area around the hatchery outlet and anywhere the water is faster will be good. Fish close with the subsurface flies since they eat and spit really fast. Sight-fishing is best. Most people wade out way too far and cast their jig & bobber rigs as far as they can and call that fly fishing. 5X-6X tippets unless the water gets dirty. Don't hesitate to go down and fish in the Niangua as well. Kreelex or similar smallmouth streamers down there.