OK Here's the way I understand it. If the guides are on the weak side of the spine you will get a little extra boost when picking up the line. Orvis does it that way. If you put the guides on the strong side you may get a little more casting power.

I think this is all subjective and either way is right.

You don't want the guides on the side of the spine some claime that that impairs casting accuracy.

Temporailly mount the guides and cast it both ways and see which you think is better. My best advice.

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Be the heron!
Mike