Hi Deb. We spent a month in southwestern CO last summer. We chose the village of Pagosa Springs. I fished the San Juan in town, east of town and south of town. Echo lake was a fun place for green perch, large mouth bass and rainbow trout. The Piedra river was a lovely fishery for Colorado cutthroat, brookies and rainbows. My favorite was William's creek and William's Creek Reservoir. There are campgrounds along the creek and at the reservoir. There are brookies, cutbows, rainbows and cutthroat and even Kokonee there. The elevation is rather high but by the time you get that far south you should be acclimated. Also the fire season should be behind you now as the monsoonal flow goes through there in July and brings some nice afternoon rain showers. The Animas river in the Durango area is another fine fishery. I think wherever you go in Colorado you will have a nice time. Jim