If i am true to myself, I only ever fish the same flies over and over again. A beaded PT nymph as my dropper and a Parachute Adams as my top fly and dry but i have alot more boxes of flies in my vest, 7 x boxes full. But those two stated are what I usually use as my go to flies and I only vary the size of the nymph, go smaller and vary the depth of dropper when fish arent biting (it works for me). I've always wanted to go minimalist, I have a double sided fly box which has only Beaded PT nymphs, size 14,16 and 18's on one side and Parachute Adams size 14 only on the other so I can use when I go Tenkara and Western fishing