It can be done, but keep in mind that Flatheads are very moody, like Muskies. It may take a lot of casting to get one to bite. Also, they are exclusively fish eaters, and not scavengers, so they won't eat any fish that does not appear to be alive. I would recommend larger clousers, and especially shad and bluegill Puglisi-style patterns, like these:

Puglisi Shad.jpgPuglisi Bluegill2.jpg

I catch Channels and Blues on these all the time, mostly behind tailraces. If you go downstream, and work these through the deeper holes, you should hook up with some Flatheads. I also put a drop of Shad, or Baitfish Smelly Jelly on the files every 20 casts or so.

Good Luck.