buy your hackle at the fly shop not online. you can handle the hackle at the fly shop for inspection and quality, you cant do that online
buy the highest quality materials you can afford
clean your tying tools. clean out the waxy build up in those bobbin holders
sit in a comfortable chair and have it at the right height to prevent soreness in your back and shoulders
have good lighting in your tying area.
keep all of your feathers in the original zip lock baggie they came in or replace ripped open baggies with new ones.
organize your tying room/area. know where everything is. label those Rubbermaid plastic shoe boxes so you'll know whats inside
practice techniques you are having a hard time with. it will get easier.
take a tying lesson. you don't know it all. yet!
head out to your local fly shop on Saturdays. most will have a tying seminar of some kind
leave your materials on the card or spool. for instance, just unwrap a few inches of chenille and the stick it back into that slot. tie in the chenille and wrap forward. tie off and cut off the chenille. no wasted material
break some thread. its the only way you'll know how much tension you can apply
untwist your thread counterclockwise to lay down a ribbon of thread in lieu of a rope.
minimize wraps of thread. it doesnt take 57 wraps of thread to tie in materials.
do you have any other tip and tricks to add??
lets try not to repeat what someone else posted