I use just a straight 20 lb fluorocarbon leader when I fish for pike on my trip to Ontario. I would use the same set-up fishing around here for chain pickerel or muskie. If I were getting bit off I'd add about a 12 inch piece of bite tippet, 30-40 lb fluoro.
As far as flies go. I'd try an all white Deceiver or a large white wooly bugger for them. Base your retrieve on the one you use with spinning tackle.

Bugman:
There are several, but Tyger Wire is the only name that comes to mind right now.