I don't have the salt water fly fishing experience of others, but I have a clouser on almost all the time. I have a lot of confidence in it. Around NJ, the conventional wisdom is char/white in stained water. If the water is clear, more natural colors are better -- olive/white, for example. I've met a lot of people who firmly belive in white/white.

The only thing about clousers is casting them. I shortened and stiffened up my leaders, and that helps. I've decided to tie all my clousers with white thread, and then use a marking pen if I want a different color. Helps with the thread inventory.